4,4'-(3,4-己烷二基)二(1,3-苯二酚)合成路线 （共 3 条）
反应条件
boron tribromide in dichloromethane
1.) -60 deg C, 0.5 h, 2.) RT, 4 h;
参考文献
Hartmann, Rolf W.; Schwarz, Walter; Schoenenberger, Helmut
Journal of Medicinal Chemistry, 1983 , vol. 26, # 8 p. 1137 - 1144
反应条件
1: 36 percent / TiCl3, LiAlH4 / 1,2-dimethoxy-ethane / 16 h / Heating
2: 68 percent / BBr3 / CH2Cl2 / 1.) -60 deg C, 0.5 h, 2.) RT, 4 h
View Scheme
参考文献
Hartmann, Rolf W.; Schwarz, Walter; Schoenenberger, Helmut
Journal of Medicinal Chemistry, 1983 , vol. 26, # 8 p. 1137 - 1144
反应条件
1: 78 percent
2: 36 percent / TiCl3, LiAlH4 / 1,2-dimethoxy-ethane / 16 h / Heating
3: 68 percent / BBr3 / CH2Cl2 / 1.) -60 deg C, 0.5 h, 2.) RT, 4 h
View Scheme
参考文献
Hartmann, Rolf W.; Schwarz, Walter; Schoenenberger, Helmut
Journal of Medicinal Chemistry, 1983 , vol. 26, # 8 p. 1137 - 1144
