3-(1-吡咯烷基)苯甲醛合成路线 (共 3 条)
反应条件
hydrogenchloride in tetrahydrofuran T=0 - 20°C; Inert atmosphere;
参考文献
ENVIVO PHARMACEUTICALS, INC.; RIPKA, Amy; SHAPIRO, Gideon; MCRINER, Andrew, J.; BURSAVICH, Matthew, Gregory
Patent: WO2013/142269 A1, 2013 ;
Location in patent: Paragraph 0581; 0582 ;
反应条件
1: tris-(dibenzylideneacetone)dipalladium(0) / toluene 2: hydrogenchloride / tetrahydrofuran / 0 - 20 °C / |Inert atmosphere View Scheme
反应条件
1: toluene-4-sulfonic acid; hydrogen / toluene / 2 h / |Reflux 2: tris-(dibenzylideneacetone)dipalladium(0) / toluene 3: hydrogenchloride / tetrahydrofuran / 0 - 20 °C / |Inert atmosphere View Scheme