1: 85.5 percent / hydrogen, 1N HCl / 10percent Pd-C / H2O; methanol / 20 h / 40 °C 2: 86.3 percent / TEA / ethanol / Ambient temperature 3: 97.7 percent / NaBH4 / ethanol / 72 h / Ambient temperature View Scheme

1: 85.5 percent / hydrogen, 1N HCl / 10percent Pd-C / H2O; methanol / 20 h / 40 °C 2: 93.2 percent / TEA / ethanol / Ambient temperature 3: 91.9 percent / NaBH4 / ethanol / 72 h / Ambient temperature View Scheme

1: 85.4 percent / diethyl ether; 1,2-dichloro-ethane / 1 h / Ambient temperature 2: 84.9 percent / 3.52 N HCl (in ethyl acetate) / CH2Cl2 / 1.5 h / Ambient temperature 3: 85.5 percent / TEA / ethanol / Ambient temperature 4: 88.6 percent / NaBH4 / ethanol / 72 h / Ambient temperature View Scheme

hydrogenchloride; hydrogen; palladium on activated charcoal in methanol; water T=40°C; 20 h;