6,7,12,13-四氢-5H-吲哚并[2,3-a]吡咯并[3,4-c]咔唑-5-酮合成路线 （共 45 条）
反应条件
1: 85 percent / iPr2NEt / CH2Cl2 / 0.08 h / 0 °C 2: 89 percent / Pd(Ph3P)4, CuI, LiCl / tetrahydrofuran / 3.5 h / Heating 3: 37 percent / acetonitrile / 1.5 h / Irradiation 4: 90 percent / EtONa / ethanol / 0.25 h / Heating 5: 92 percent Turnov. / NaBH4, CoCl2*6H2O / methanol; tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 54, # 24 p. 6909 - 6918
反应条件
1: 78 percent / Me2NH / CH2Cl2 / 0.17 h / Ambient temperature 2: 85 percent / iPr2NEt / CH2Cl2 / 0.08 h / 0 °C 3: 89 percent / Pd(Ph3P)4, CuI, LiCl / tetrahydrofuran / 3.5 h / Heating 4: 37 percent / acetonitrile / 1.5 h / Irradiation 5: 90 percent / EtONa / ethanol / 0.25 h / Heating 6: 92 percent Turnov. / NaBH4, CoCl2*6H2O / methanol; tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 54, # 24 p. 6909 - 6918
反应条件
1: 90 percent / EtONa / ethanol / 0.25 h / Heating 2: 92 percent Turnov. / NaBH4, CoCl2*6H2O / methanol; tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 54, # 24 p. 6909 - 6918
反应条件
1: 99 percent / EtONa / ethanol / 0.5 h / Heating 2: 92 percent Turnov. / NaBH4, CoCl2*6H2O / methanol; tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 54, # 24 p. 6909 - 6918
反应条件
1: 37 percent / acetonitrile / 1.5 h / Irradiation 2: 90 percent / EtONa / ethanol / 0.25 h / Heating 3: 92 percent Turnov. / NaBH4, CoCl2*6H2O / methanol; tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 54, # 24 p. 6909 - 6918
反应条件
1: 92 percent / NH4OAc / 150 °C 2: 58 percent / Zn(Hg), 5N HCl / ethanol; toluene / 1.5 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 35, # 31 p. 5555 - 5558
反应条件
1: 83 percent / acetic anhydride / tetrahydrofuran 2: 1.) PhBr, 2.) O2 / 1.) reflux 3: triethyl phosphite / tetrahydrofuran / Heating View Scheme
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 23 p. 1667 - 1668
反应条件
1: 1.) PhBr, 2.) O2 / 1.) reflux 2: triethyl phosphite / tetrahydrofuran / Heating View Scheme
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 23 p. 1667 - 1668
反应条件
1: 97 percent / aq. KOH / tetrahydrofuran; methanol 2: 83 percent / acetic anhydride / tetrahydrofuran 3: 1.) PhBr, 2.) O2 / 1.) reflux 4: triethyl phosphite / tetrahydrofuran / Heating View Scheme
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 23 p. 1667 - 1668
反应条件
1: 72 percent / toluene-p-sulphonic acid / CH2Cl2 / 15 h / Ambient temperature 2: 54 percent / triphenylphosphine / various solvent(s) / 40 h / Heating 3: 80 percent / 2M H2SO4 / tetrahydrofuran / 2 h / 50 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 9 p. 2475 - 2480
