4-(4-联苯基)-2,4-二氧代丁酸合成路线 （共 2 条）
反应条件
1: With sodium methylate in tetrahydrofuran; methanol
T=20°C; Claisen condensation; 2 h;
2: With sodium hydroxide in tetrahydrofuran; methanol
4 h;
参考文献
Tumey, L. Nathan; Huck, Bayard; Gleason, Elizabeth; Wang, Jianmin; Silver, Daniel; Brunden, Kurt; Boozer, Sherry; Rundlett, Stephen; Sherf, Bruce; Murphy, Steven; Bailey, Andrew; Dent, Tom; Leventhal, Christina; Harrington, John; Bennani, Youssef L.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 19 p. 4915 - 4918
反应条件
sodium hydroxide in 1,4-dioxane; ethanol
Ambient temperature; Yield given;
参考文献
Williams, H. W. R.; Eichler, E.; Randall, W. C.; Rooney, C. S.; Cragoe, E. J.; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 8 p. 1196 - 1200
