cesium fluoride in N,N-dimethyl-formamide T=25°C; 24 h;

1: 4,4'-dimethyl-2,2'-bipyridine With lithium diisopropyl amide in tetrahydrofuran; hexane 2 h; Inert atmosphere; 2: n-dodecyl iodide in tetrahydrofuran; hexane T=0°C; 1.5 h; Inert atmosphere;

n-butyllithium; diisopropylamine in tetrahydrofuran; hexane 1.) 0 deg C, 1 h, 2.) 0 deg C, 30 min; 25 deg C, overnight;

1: 1.) LDA / 1.) THF, -78 deg C, 20 min; -78 deg C to -10 deg C, 25 min, 2.) -78 deg C, 10 s 2: 13 percent Chromat. / CsF / dimethylformamide / 24 h / 25 °C View Scheme

n-butyllithium; diisopropylamine in tetrahydrofuran; hexane 12 h; Ambient temperature;