4-溴-N,N-二甲基-1-[三(1-甲基乙基)硅酯]-1H-吡咯并[2,3-B]吡啶-3-甲胺合成路线 (共 1 条)
反应条件
1: With tert.-butyl lithium in hexanes; diethyl ether
T=-78 - 20°C;
2: With ethylene dibromide in hexanes; diethyl ether
T=-78 - 20°C; 2 - 3 h;
3: With water in hexanes; diethyl ether
参考文献
Plexxikon, Inc.
Patent: US2007/49615 A1, 2007 ;
Location in patent: Page/Page column 66 ;