N-BOC-1,2,3,6-四氢吡啶合成路线 （共 32 条）
反应条件
1: sodium hydrogencarbonate / ethanol; water / 4.5 h / 20 °C 2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 2 h / 0 °C 3: caesium carbonate / dimethyl sulfoxide / 3 h / 120 °C View Scheme
参考文献
Tetrahedron, , vol. 67, # 7 p. 1485 - 1500
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 2 h / 0 °C 2: caesium carbonate / dimethyl sulfoxide / 3 h / 120 °C View Scheme
参考文献
Tetrahedron, , vol. 67, # 7 p. 1485 - 1500
反应条件
1: triethylamine / dichloromethane / 8 h / 20 °C 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 150 °C View Scheme
反应条件
1: sodium hydrogencarbonate / ethanol; water / 4.5 h / 20 °C 2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 2 h / 0 °C 3: caesium carbonate / dimethyl sulfoxide / 120 °C View Scheme
参考文献
Tetrahedron, , vol. 67, # 7 p. 1485 - 1500
反应条件
1: sodium hydrogencarbonate / ethanol; water / 4.5 h / 20 °C 2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 2 h / 0 °C 3: caesium carbonate / dimethyl sulfoxide / 120 °C View Scheme
参考文献
Tetrahedron, , vol. 67, # 7 p. 1485 - 1500
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 2 h / 0 °C 2: caesium carbonate / dimethyl sulfoxide / 120 °C View Scheme
参考文献
Tetrahedron, , vol. 67, # 7 p. 1485 - 1500
反应条件
1: sodium carbonate / tetrahydrofuran; water / 0 - 20 °C 2: triethylamine / dichloromethane / 8 h / 20 °C 3: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 150 °C View Scheme
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 14 h / 0 - 20 °C 2: trimethylsilyl iodide / N,N-dimethyl-formamide / 20 °C / |Cooling with ice 3: pyridinium p-toluenesulfonate / dichloromethane / 20 °C 4: 1,8-diazabicyclo[5.4.0]undec-7-ene / 27 h / 80 °C 5: hydrogenchloride / dichloromethane; ethyl acetate; methanol / 0 - 20 °C View Scheme
参考文献
XI, Ning; WANG, Tingjin; YI, Lei
Patent: WO2013/138210 A1, 2013 ;
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 14 h / 0 - 20 °C 2: trimethylsilyl iodide / N,N-dimethyl-formamide / 20 °C / |Cooling with ice 3: pyridinium p-toluenesulfonate / dichloromethane / 20 °C 4: 1,8-diazabicyclo[5.4.0]undec-7-ene / 27 h / 80 °C 5: hydrogenchloride / dichloromethane; ethyl acetate; methanol / 0 - 20 °C 6: Dess-Martin periodane / dichloromethane / 2 h / 20 °C View Scheme
参考文献
XI, Ning; WANG, Tingjin; YI, Lei
Patent: WO2013/138210 A1, 2013 ;
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane
参考文献
Boto, Alicia; Hernandez, Rosendo; De Leon, Yolanda; Murguia, Jose R.; Rodriguez-Afonso, Abigail
Tetrahedron Letters, 2004 , vol. 45, # 37 p. 6841 - 6845
