1: 68 percent / K2CO3 / acetone; dimethylformamide / 18 h / Heating 2: 1.) BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, RT, 18 h 3: conc. HCl / ethanol / 1 h / Heating View Scheme

1: 68 percent / K2CO3 / acetone; dimethylformamide / 18 h / Heating 2: 1.) BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, RT, 18 h 3: conc. HCl / ethanol / 1 h / Heating View Scheme

1: 93 percent / K2CO3 / acetone / 3 h / Heating 2: 1.) BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, RT, 18 h 3: conc. HCl / ethanol / 1 h / Heating 4: 1.) OsO4, 2.) H2S / 1.) THF, RT, 18 h View Scheme