2-羟基-6-硝基-喹啉-3-甲酸合成路线 （共 7 条）
反应条件
hydrogenchloride; sodium hydroxide
1.25 h; Heating;
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
1: 48.5 g / H2 / Raney Ni / ethanol
2: 10.7 g / 96percent H2SO4, 70percent HNO3 / 1 h / 0 °C
3: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating
View Scheme
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
1: 63 percent / KHCO3 / acetic anhydride / 2 h / Heating
2: 48.5 g / H2 / Raney Ni / ethanol
3: 10.7 g / 96percent H2SO4, 70percent HNO3 / 1 h / 0 °C
4: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating
View Scheme
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
1: 0.92 g / aq. HCl / 1.5 h / Heating
2: 0.18 g / 17.5 h / 150 - 160 °C
3: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating
View Scheme
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
1: 0.18 g / 17.5 h / 150 - 160 °C
2: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating
View Scheme
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
1: 10.7 g / 96percent H2SO4, 70percent HNO3 / 1 h / 0 °C
2: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating
View Scheme
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
hydrogen; nickel in N,N-dimethyl-formamide
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
