NiCRA-bpy in tetrahydrofuran T=65°C; 17 h; Yield given;

NiCRA-bpy (4/2/1/2) in ethylene glycol dimethyl ether T=65°C; 26 h; Title compound not separated from byproducts;

3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid in dichloromethane 1 h; Ambient temperature;

in chloroform T=75°C; 16 h;

hydrogenchloride

1: 1.) lithium 1-(dimethylamino)naphthalenide / 1.) THF, 15 min, -78 deg C 2: 1.) lithium 1-(dimethylamino)naphthalenide / 1.) THF, 4 min, -78 deg C; 2.) 15 min 3: 89 percent / KH / tetrahydrofuran / 1.5 h / 25 °C View Scheme