2-环丙基-6-氧代-1,6-二氢-嘧啶-4-羧酸合成路线 （共 2 条）
反应条件
1: diethyl 2-oxosuccinate sodium salt With water; sodium hydroxide
0.333333 h;
2: cyclopropanecarboximidamide hydrochloride in water
T=70°C;
3: With hydrogenchloride in water
T=20°C; pH=1;
参考文献
SYNGENTA LIMITED; SYNGENTA PARTICIPATIONS AG; WHITTINGHAM, William, Guy; WINN, Caroline, Louise; GLITHRO, Harry; BOUSSEMGHOUNE, Mohamed, Abdelouahab; ASPINALL, Mary, Bernadette
Patent: WO2010/92339 A1, 2010 ;
Location in patent: Page/Page column 83-84 ;
反应条件
hydrogenchloride; sodium hypochlorite in water
T=15 - 20°C;
参考文献
SYNGENTA LIMITED; SYNGENTA PARTICIPATIONS AG; WHITTINGHAM, William, Guy; WINN, Caroline, Louise; GLITHRO, Harry; BOUSSEMGHOUNE, Mohamed, Abdelouahab; ASPINALL, Mary, Bernadette
Patent: WO2010/92339 A1, 2010 ;
Location in patent: Page/Page column 84 ;
