2,3-二甲氧基苯甲醛合成路线 （共 174 条）
反应条件
1: 5 h / 100 °C 2: sodium tetrahydroborate / methanol / 4 h View Scheme
参考文献
Wang, Yan-Xiang; Li, Yu-Huan; Li, Ying-Hong; Gao, Rong-Mei; Wang, Hui-Qiang; Liu, Yan-Xin; Gao, Li-Mei; Lu, Qiao-Ni; Jiang, Jian-Dong; Song, Dan-Qing
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5787 - 5790
反应条件
1: alcoholic KOH-solution 2: diluted hydrobromic acid 3: NaOH-solution View Scheme
参考文献
Perkin; Stoyle
Journal of the Chemical Society, 1923 , vol. 123, p. 3174
反应条件
1: 86 percent / n-BuLi / tetrahydrofuran; hexane / Ambient temperature; 1.) 3 h, 2.) overnight 2: 41 percent / Jones reagent / acetone / 5 °C 3: 93 percent / 60 percent HBr / acetic acid / 6 h / Heating 4: 88 percent / CH3COOH, CH3COONa, hydroquinone / H2O / 17 h / 220 °C View Scheme
参考文献
Cox, Brian G.; Hurwood, Tracey V.; Prodi; Montalti; Bolletta; Watt, C. Ian F.
Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 2 p. 289 - 296
反应条件
lithium chloride in N,N-dimethyl-formamide 22 h; Heating;
参考文献
Bernard, Angela M.; Ghiani, M. Rossella; Piras, Pier Paolo; Rivoldini, Antonio
Synthesis, 1989 , # 4 p. 287 - 289
反应条件
1: diethyl ether 2: aq. Na2Cr2O7, H2SO4 3: AlCl3 / toluene 4: Zn-Hg, aq. HCl / ethanol 5: aq. (KO3S)2NO / ethanol View Scheme
参考文献
Schildknecht,H.; Schmidt,H.
Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, 1967 , vol. 22b, p. 287 - 294
反应条件
1: permanganate 2: hydrogen iodide / 100 °C 3: aqueous-alcoholic KOH-solution; hydrogen stream 4: thionyl chloride 5: benzene; ammonia 6: thionyl chloride View Scheme
参考文献
Perkin; Trikojus
Journal of the Chemical Society, 1926 , p. 2932
反应条件
1: diethyl ether 2: aq. Na2Cr2O7, H2SO4 3: AlCl3 / toluene 4: Zn-Hg, aq. HCl / ethanol View Scheme
参考文献
Schildknecht,H.; Schmidt,H.
Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, 1967 , vol. 22b, p. 287 - 294
反应条件
1: Heating 2: 93 percent / H2 / Pd/C 3: 60 percent / aq. HCl View Scheme
参考文献
Leseche, Bernard; Gilbert, Jacques; Viel, Claude
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 143 - 153
反应条件
1: tetrahydrofuran / 8 h / 20 - 40 °C 2: LiAlH4 / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Artyushin, O. I.; Petrovskii, P. V.; Mastryukova, T. A.; Kabachnik, M. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1991 , vol. 40, # 9.2 p. 1911 - 1913
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1991 , # 9 p. 2154 - 2157
反应条件
1: 62 percent / KMnO4, 10percent aq. NaOH / 1.) 50 deg C, 1 h; 2.) room temp., 12 h. 2: SOCl2 / benzene / Heating; overnight 3: conc. NH4OH / ice bath temperature View Scheme
参考文献
Stuart; Khora; McKenney Jr.; Castle
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 6 p. 1589 - 1594
