2,3-二甲氧基苯甲醛合成路线 （共 174 条）
反应条件
1: ammonium acetate / 3 h / Heating 2: LiAlH4 / tetrahydrofuran / 4 h / Ambient temperature 3: benzene / Heating 4: NaBH4 / ethanol / 0.5 h / Ambient temperature View Scheme
参考文献
Kubo, Akinori; Saito, Naoki; Kawakami, Nanko; Matsuyama, Yasuo; Miwa, Teruyo
Synthesis, 1987 , # 9 p. 824 - 827
反应条件
1: sodium; ethyl acetate; ethanol 2: copper oxide-chromium oxide / 225 °C / 139746 Torr / Hydrogenation View Scheme
参考文献
Mason
Journal of the American Chemical Society, 1947 , vol. 69, p. 2241
反应条件
1: Ag2O; aqueous NaOH 2: concentrated H2SO4; 1,2-dichloro-ethane 3: diethyl ether View Scheme
参考文献
Edwards; Cashaw
Journal of Organic Chemistry, 1955 , vol. 20, p. 847
反应条件
1: 57 percent / methanol / -10 °C 2: 63 percent / xylene / Heating 3: 93 percent / aq. NaOH / Heating 4: 83 percent / Cu; quinoline / Heating 5: 57 percent / phosphoryl chloride / 0 - 40 °C View Scheme
参考文献
Coowar, Djalil; Bouissac, Julien; Hanbali, Mazen; Paschaki, Marie; Mohier, Eliane; Luu, Bang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6270 - 6282
反应条件
1: 98 percent / 4percent piperidine / pyridine / Heating 2: 80 percent / H2 / 5percent Pd/C / ethyl acetate / 40 °C / 2068.6 Torr View Scheme
参考文献
Perkin; Robinson
Journal of the Chemical Society, 1914 , vol. 105, p. 2384
反应条件
1: diethyl ether / 2 h / Heating 2: Na2Cr2O7; aq. H2SO4 / acetone / 3 h / 20 °C 3: 228 mg / BBr3 / CH2Cl2 / 20 °C View Scheme
参考文献
Albrecht, Markus; Mirtschin, Sebastian; De Groot, Marita; Janser, Ingo; Runsink, Jan; Raabe, Gerhard; Kogej, Michael; Schalley, Christoph A.; Froehlich, Roland
Journal of the American Chemical Society, 2005 , vol. 127, # 29 p. 10371 - 10387
反应条件
zirconium hydrogenphosphate T=90°C; Biginelli pyrimidine synthesis; 1 h; Neat (no solvent);
参考文献
Besoluk, Senol; Kucukislamoglu, Mustafa; Zengin, Mustafa; Arslan, Mustafa; Nebioglu, Mehmet
Turkish Journal of Chemistry, 2010 , vol. 34, # 3 p. 411 - 416
反应条件
1: 57 percent / methanol / -10 °C 2: 63 percent / xylene / Heating 3: 93 percent / aq. NaOH / Heating 4: 83 percent / Cu; quinoline / Heating View Scheme
参考文献
De Luca, Laura; De Grazia, Sara; Ferro, Stefania; Gitto, Rosaria; Christ, Frauke; Debyser, Zeger; Chimirri, Alba
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 756 - 764
反应条件
ammonium acetate in butan-1-ol Rodionov reaction; Heating;
参考文献
Lebedev; Lebedeva; Sheludyakov; Kovaleva; Ustinova; Kozhevnikov
Russian Journal of General Chemistry, 2005 , vol. 75, # 7 p. 1113 - 1124
参考文献
Dallemagne, Patrick; Rault, Sylvain; Pilo, Juan Carlos; Foloppe, Marie Paule; Robba, Max
Tetrahedron Letters, 1991 , vol. 32, # 44 p. 6327 - 6328
