3,4,5-三甲氧基苯甲醛合成路线 （共 427 条）
反应条件
1: NaBH4 / methanol / 20 °C 2: SOCl2 / dioxane / 20 °C View Scheme
参考文献
Cook et al.
Journal of the Chemical Society, 1944 , p. 322,324
反应条件
1: 47 percent / 10-camphorsulfonic acid / 16 h / 65 °C 2: 69 percent / POCl3; Et3N / 1,2-dimethoxy-ethane / 3 h / -5 °C View Scheme
参考文献
Wang, Le; Woods, Keith W.; Li, Qun; Barr, Kenneth J.; McCroskey, Richard W.; Hannick, Steven M.; Gherke, Laura; Credo, R. Bruce; Hui, Yu-Hua; Marsh, Kennan; Warner, Robert; Lee, Jang Y.; Zielinski-Mozng, Nicolette; Frost, David; Rosenberg, Saul H.; Sham, Hing L.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 8 p. 1697 - 1711
反应条件
1: camphor-10-sulfonic acid / 16 h / 65 °C 2: trichlorophosphate; triethylamine / ethylene glycol dimethyl ether / 3 h / -10 - -5 °C View Scheme
参考文献
Chaudhary, Anurag; Sharma; Bhardwaj, Gautam; Jain, Vaibhav; Bharatam; Shrivastav, Birendra; Roy
Medicinal Chemistry Research, 2013 , vol. 22, # 12 p. 5654 - 5669
反应条件
aluminium(III) iodide; tetra-(n-butyl)ammonium iodide in cyclohexane 6 h; other reaction time, other molar ratios of educt/AlI3 and educt/catalyst; Product distribution;
参考文献
Andersson, Sven
Synthesis, 1985 , # 4 p. 437 - 439
反应条件
1: NaBH3CN, AcOH / 16 h / Ambient temperature 2: aq. KOH / ethanol / 2.5 h / 130 °C View Scheme
参考文献
Ferte, Jacques; Kuehnel, Jean-Marc; Chapuis, Genevieve; Rolland, Yves; Lewin, Guy; Schwaller, Marc A.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 3 p. 478 - 489
反应条件
1: With sodium hydride in ethanol; benzene T=20°C; Horner-Wadsworth-Emmons type reaction; 18 h; Inert atmosphere; 2: With hydrogenchloride; water in methanol T=20°C; 1 h;
参考文献
Roman, Bart I.; Ryck, Tine De; Dierickx, Laura; Vanhoecke, Barbara W.A.; Katritzky, Alan R.; Bracke, Marc; Stevens, Christian V.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 15 p. 4812 - 4819
反应条件
1: 97 percent / hydrazine hydrate; KOH / ethane-1,2-diol / 6 h / 70 - 120 °C 2: 95 percent / POCl3 / 5 h / 65 °C 3: aq.H2SO4; aq.H2O2 / methanol / 10 - 20 °C View Scheme
参考文献
Wang, Jin; Yang, Jian; Yang, Bo; Sun, Jia-Qiang; Yang, Tao
Journal of Chemical Research, 2010 , vol. 34, # 12 p. 724 - 725
反应条件
1: 97 percent / H2 / 10percent Pd/C / acetic acid / 72 h / 30002.4 Torr / Ambient temperature 2: 96 percent / 57percent HI, 30percent aq. H3PO2 / Heating 3: 82 percent / molecular sieves 4 Angstroem / Amberlite IR 120-plus / benzene / Heating 4: K2CO3 / Bu4NHSO4 / acetone / 24 h / Heating 5: TsOH / methanol; H2O / 16 h / Ambient temperature 6: 91 percent / K2CO3 / acetone / 15 h / Heating 7: 96 percent / H2 / 10percent Pd/C / tetrahydrofuran / 6 h / Ambient temperature 8: 92 percent / K2(SO3)2NO, KH2SO4 / benzene; H2O / 3 h / Ambient temperature View Scheme
参考文献
Chida; Vani; Chandrasekharam; Srinivasan; Singh
Synthetic Communications, 2001 , vol. 31, # 5 p. 657 - 660
反应条件
1: 97 percent / hydrazine hydrate; KOH / ethane-1,2-diol / 6 h / 70 - 120 °C 2: 95 percent / POCl3 / 5 h / 65 °C 3: aq.H2SO4; aq.H2O2 / methanol / 10 - 20 °C 4: 17.6 g / benzene; polyglycol-400; aq.NaOH / H2O / 2.5 h / 55 °C / pH 9.0 - 9.5 View Scheme
参考文献
Wang, Jin; Yang, Jian; Yang, Bo; Hu, Xiao; Sun, Jia-Qiang; Yang, Tao
Journal of Chemical Research, 2010 , vol. 34, # 12 p. 717 - 718
反应条件
silica-bonded N-propylpiperazine sulfamic acid #10;#10; in ethanol T=20°C; 0.0833333 h;
参考文献
Rahi, Tahere; Baghernejad, Mojtaba; Niknam, Khodabakhsh
Chinese Chemical Letters, 2012 , vol. 23, # 10 p. 1103 - 1106,4
