3,4,5-三甲氧基苯甲醛合成路线 （共 427 条）
反应条件
hydroxylamine hydrochloride; potassium carbonate in methanol T=20°C;
参考文献
Hou, Yingwei; Lu, Shichao; Liu, Gang
Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8386 - 8395
反应条件
1: sodium acetate / acetic anhydride / Heating 2: NaOH / H2O / Heating 3: hydroxylamine hydrochloride / aq. NaOH / 0.5 h / 60 °C 4: acetic anhydride / 0.08 h / Heating 5: ZnCl2, HCl / diethyl ether / 5 h / 0 °C 6: 2.0 g / aq. potassium persulphate / aq. KOH / Ambient temperature 7: K2CO3 / acetone / 50 h / Heating 8: 1) Na, 2) conc.hydrochloric acid / 1) r.t., 2) heating, 15-20 min. View Scheme
参考文献
Shaw; Srivastava; Jha
Journal of the Indian Chemical Society, 1990 , vol. 67, # 2 p. 144 - 147
反应条件
piperidine in acetic acid 0.0333333 h; microwave irradiation;
参考文献
Chemistry Letters, , vol. 32, # 12 p. 1186 - 1187
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; Wittig reaction; 16 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 15, # 1 p. 518 - 525
反应条件
pyridine; acetic acid T=130°C; Knoevenagel-Doebner reaction; 0.133333 h; microwave irradiation;
参考文献
Tetrahedron, , vol. 63, # 4 p. 960 - 965
反应条件
ammonium acetate in butan-1-ol Rodionov reaction; Heating;
参考文献
Russian Journal of General Chemistry, , vol. 75, # 7 p. 1113 - 1124
反应条件
1: benzene / 3 h / 20 °C 2: water; lithium hydroxide hydrate / tetrahydrofuran / 12 h / 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 57, p. 344 - 361
反应条件
1: 1.) butyllithium / 1.) THF, RT, 20 min, 2.) THF, 10 min 2: 93 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.33 h 3: 94.4 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme
参考文献
Getahun, Zelleka; Jurd, Leonard; Chu, Ping S.; Lin, Chii M.; Hamel, Ernest
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1058 - 1067
反应条件
1: 3,4,5-trimethoxy-benzaldehyde; 2-(3,4-dimethoxyphenyl)-ethylamine With formic acid T=110°C; Pictet-Spengler reaction; 2: formaldehyd With formic acid Heating;
参考文献
Ruchirawat, Somsak; Bhavakul, Vanida; Chaisupakitsin, Malinee
Synthetic Communications, 2003 , vol. 33, # 4 p. 621 - 625
反应条件
1: benzene / 5 h / Heating 2: 36.2 percent / n-Bu3SnH, AIBN / toluene / Heating 3: 94.8 percent / NaBH4 / methanol; H2O View Scheme
参考文献
Takano, Seiichi; Suzuki, Mahito; Kijima, Atsushi; Ogasawara, Kunio
Chemistry Letters, 1990 , # 2 p. 315 - 316
