3,4,5-三甲氧基苯甲醛合成路线 （共 427 条）
反应条件
sodium methylate in N,N-dimethyl-formamide T=0 - 100°C; Wittig-Horner olefination; 4 h; Inert atmosphere;
参考文献
Das, Joydip; Pany, Satyabrata; Majhi, Anjoy
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5321 - 5333
反应条件
pyridine; titanium tetrachloride; zinc in 1,4-dioxane 0.133333 h; microwave irradiation;
参考文献
Ramana; Singh; Parihar
Journal of Chemical Research, 2004 , # 11 p. 760 - 761
反应条件
lithium methanolate in methanol; N,N-dimethyl-formamide T=90°C; 1 h; Title compound not separated from byproducts;
参考文献
Mervic, Miljenko; Ghera, Eugene
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4720 - 4725
反应条件
n-butyllithium 1.) THF, hexane, 0 deg C, 10 min; 2.) THF, r.t., 12 h; Yield given. Multistep reaction;
参考文献
Brown; Brown, Karen M.; Lawrence; Lawrence, Nicholas J.; Liddle; Liddle, John; Muhammad; Muhammad, Faiz; Jackson; Jackson, David A.
Tetrahedron Letters, 1994 , vol. 35, # 36 p. 6733 - 6736
反应条件
1: 60 percent / n-butyl lithium / tetrahydrofuran / 3 h / -78 °C 2: HgO, BF3*OEt2 / 28 h View Scheme
参考文献
Hadimani, Shreeshailkumar B.; Tanpure, Rajendra P.; Bhat, Sujata V.
Tetrahedron Letters, 1996 , vol. 37, # 27 p. 4791 - 4794
反应条件
1: 97 percent / H2 / 10percent Pd/C / acetic acid / 72 h / 30002.4 Torr / Ambient temperature 2: 96 percent / 57percent HI, 30percent aq. H3PO2 / Heating View Scheme
参考文献
Asahina; Yasue
Chemische Berichte, 1936 , vol. 69, p. 2327,2328
Yakugaku Zasshi, 1937 , vol. 57, p. 455,457
反应条件
1: NaOMe / dimethylsulfoxide 2: DMSO / ethanol View Scheme
参考文献
Manchand, Percy S.; Rosen, Perry; Belica, Peter S.; Oliva, Gloria V.; Perrotta, Agostino V.; Wong, Harry S.
Journal of Organic Chemistry, 1992 , vol. 57, # 13 p. 3531 - 3535
反应条件
formic acid; triethylamine in ethanol
参考文献
BIOGAL GYOGYSZERGYAR
Patent: EP578850 A1, 1994 ;
反应条件
1: 1) piperidine, 2) conc. H2SO4 / 1) pyridine 2: hydrogen / 5percent Pd/C / ethanol View Scheme
参考文献
Brown; Blakemore; Durant; Emmett; Ganellin; Parsons; Rawlings; Walker
European Journal of Medicinal Chemistry, 1988 , vol. 23, # 1 p. 53 - 62
反应条件
montmorillonite K10 in methanol T=40°C; 18 h; Inert atmosphere;
参考文献
Laurent, Mathieu Y.; Stocker, Vivien; Temgoua, Valery Momo; Dujardin, Gilles; Dhal, Robert
Tetrahedron Letters, 2011 , vol. 52, # 14 p. 1608 - 1611
