3,4,5-三甲氧基苯甲醛合成路线 （共 427 条）
反应条件
Fe(ClO4)3*xH2O; dihydrogen peroxide in water T=0 - 20°C; 20 h;
参考文献
Wu, Xiao-Feng; Darcel, Christophe
European Journal of Organic Chemistry, 2009 , # 8 p. 1144 - 1147
反应条件
lithium diisopropyl amide in tetrahydrofuran T=-78°C; 2 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 10 p. 4333 - 4337
反应条件
1: 87 percent / montmorillonite K 10 / methanol / 72 h / Ambient temperature 2: 1.) BF3*Et2O; 2.) silica gel / 1.) CH2Cl2, -78 deg C, 3 h; 2.) toluene, reflux, overnight View Scheme
参考文献
Laurent, Mathieu Y.; Stocker, Vivien; Temgoua, Valery Momo; Dujardin, Gilles; Dhal, Robert
Tetrahedron Letters, 2011 , vol. 52, # 14 p. 1608 - 1611
反应条件
sodium hydride in tetrahydrofuran T=20°C; Wittig reaction; 5 h;
参考文献
Sun, Bin; Hoshino, Juma; Jermihov, Katie; Marler, Laura; Pezzuto, John M.; Mesecar, Andrew D.; Cushman, Mark
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 14 p. 5352 - 5366
反应条件
1: triphenyl-methyl-phosphonium iodide With n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C; Wittig Olefination; 2: 3,4,5-trimethoxy-benzaldehyde in tetrahydrofuran; hexane T=-78 - 20°C;
参考文献
Bosiak, Mariusz J.; Rakowiecki, Marcin; Orlowska, Katarzyna J.; Kedziera, Dariusz; Adams, Joerg
Dyes and Pigments, 2013 , vol. 99, # 3 p. 803 - 811
反应条件
pyridine; acetic acid T=130°C; Knoevenagel-Doebner reaction; 0.133333 h; microwave irradiation;
参考文献
Sinha, Arun K.; Sharma, Anuj; Joshi, Bhupendra P.
Tetrahedron, 2007 , vol. 63, # 4 p. 960 - 965
反应条件
1: n-butyllithium / tetrahydrofuran / -78 - 20 °C 2: copper (II) acetate monohydrate; potassium tert-butylate; 1,3-bis(2,6-diisopropylphenyl)imidazolinium chloride; tert-butyl alcohol / toluene / 3 h / 24 °C / |Inert atmosphere View Scheme
参考文献
Wang, Guang-Hui; Bin, Huai-Yu; Sun, Miao; Chen, Shu-Wei; Liu, Ji-Hong; Zhong, Chong-Min
Tetrahedron, 2014 , vol. 70, # 12 p. 2175 - 2179
反应条件
Multistep reaction.;
参考文献
Hansen, Anne-Lene L.; Murray, Anthony; Tanner, David
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 24 p. 4497 - 4505
反应条件
1: benzene / 3 h / 20 °C 2: water; lithium hydroxide hydrate / tetrahydrofuran / 12 h / 20 °C 3: triethylamine / tetrahydrofuran / 0.75 h / -20 °C 4: triethylamine / dichloromethane / 2 h / 20 °C View Scheme
参考文献
Rao, Vidadala Ramasubba; Muthenna, Puppala; Shankaraiah, Gundeti; Akileshwari, Chandrasekhar; Babu, Kothapalli Hari; Suresh, Ganji; Babu, Katragadda Suresh; Chandra Kumar, Rotte Sateesh; Prasad, Kothakonda Rajendra; Yadav, Potharaju Ashok; Petrash, J. Mark; Reddy, Geereddy Bhanuprakash; Rao, Janaswamy Madhusudana
European Journal of Medicinal Chemistry, 2012 , vol. 57, p. 344 - 361
反应条件
1: 87 percent / NH4OAc / 7 h / 105 °C 2: 65 percent / H2, glacial AcOH / Raney Ni / 15 h / 25 °C View Scheme
参考文献
Frost,D.A.; Morrison,G.A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 2388 - 2396
