3,4,5-三甲氧基苯甲醛合成路线 （共 427 条）
反应条件
1: isopropylmagnesium chloride / tetrahydrofuran / -78 - 0 °C / Inert atmosphere 2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide / 19 h / 20 °C 3: dimethyl sulfoxide / 60 h / 40 °C View Scheme
参考文献
Zall, Andrea; Bensinger, Dennis; Schmidt, Boris
European Journal of Organic Chemistry, 2012 , # 7 p. 1439 - 1447
反应条件
1: With trifluoroacetic acid in dichloromethane T=20°C; 2 h; 2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane T=20°C; 2 h;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 11 p. 3293 - 3304
反应条件
silica-bonded N-propylpiperazine sulfamic acid in ethanol T=20°C; 0.0833333 h;
参考文献
Rahi, Tahere; Baghernejad, Mojtaba; Niknam, Khodabakhsh
Chinese Chemical Letters, 2012 , vol. 23, # 10 p. 1103 - 1106,4
反应条件
aluminium(III) iodide; tetra-(n-butyl)ammonium iodide in cyclohexane 6 h; other reaction time, other molar ratios of educt/AlI3 and educt/catalyst; Product distribution;
参考文献
Andersson, Sven
Synthesis, 1985 , # 4 p. 437 - 439
反应条件
1: 65 percent / piperidine / H2O / 20 h / Heating 2: pyridine 3: 73 percent / benzene / 48 h / Heating 4: 100 percent / 90percent trifluoroacetic acid / 0.17 h / Ambient temperature 5: 92 percent / potassium acetate / 0.17 h / Heating View Scheme
参考文献
Rizzacasa, Mark A.; Sargent, Melvyn V.
Australian Journal of Chemistry, 1987 , vol. 40, # 10 p. 1737 - 1743
反应条件
1: potassium tert-butylate / toluene 2: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran / 55 °C View Scheme
参考文献
Hung, Hsin-Yi; Ohkoshi, Emika; Goto, Masuo; Nakagawa-Goto, Kyoko; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7726 - 7729
反应条件
in tetrahydrofuran; dimethyl sulfoxide 1.) 0-5 deg C, 15 min., 2.) r.t., 90 min; Yield given;
参考文献
Alvarez; Granados; Lavilla; Salas
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 3 p. 745 - 750
反应条件
in methanol 0.5 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, # 1 p. 89 - 96
反应条件
1: 92 percent / methanol / 0.5 h / Heating 2: 84 percent / methanol / 100 °C 3: 0.6 g / 50 percent aq. acetic acid / 0.25 h / 100 °C 4: HCl / Heating View Scheme
参考文献
Jurd
Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 1 p. 89 - 96
反应条件
1: 92 percent / methanol / 0.5 h / Heating 2: 68 percent / methanol / 0.5 h / 100 °C 3: 98 percent / glacial acetic acid / H2O / 1 h / 100 °C 4: 0.12 g / conc. hydrochloric acid / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, # 1 p. 89 - 96
