4-甲氧基-2-硝基苯基硼酸合成路线 （共 3 条）
反应条件
1: 1-iodo-4-methoxy-2-nitrobenzene With phenyl-magnesium chloride in tetrahydrofuran
T=-70 - 60°C; 0.416667 h;
2: boric acid trimethyl ester in tetrahydrofuran
T=-60°C; 1 h;
3: With hydrogenchloride; water in tetrahydrofuran
T=-20 - 20°C;
参考文献
TIBOTEC PHARMACEUTICALS LTD.; MEDIVIR AB
Patent: WO2007/14922 A1, 2007 ;
Location in patent: Page/Page column 126 ;
反应条件
1: With phenyl-magnesium chloride in tetrahydrofuran
T=-60°C; 0.0833333 h;
2: With boric acid trimethyl ester in tetrahydrofuran
T=-60°C; 0.5 h;
3: With hydrogenchloride in tetrahydrofuran
T=-20°C;
参考文献
Collibee, Scott E.; Yu, Jiaxin
Tetrahedron Letters, 2005 , vol. 46, # 26 p. 4453 - 4455
反应条件
hydrogenchloride in tetrahydrofuran
参考文献
Harper, Steven; Summa, Vincenzo; Liverton, Nigel J.; McCauley, John A.; Butcher, John W.; Di Filippo, Marcello; Di Francesco, Maria Emilia; Ferrara, Marco; Romano, Joseph J.; Rudd, Michael T.
Patent: US2010/183551 A1, 2010 ;
