5-苯基-1H-吲哚-7-羧酰胺合成路线 （共 4 条）
反应条件
hydrogenchloride in ethanol; water
T=150°C; 0.0833333 h; Microwave;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2005/67923 A1, 2005 ;
Location in patent: Page/Page column 66-67 ;
WO 2005/067923 A1
反应条件
hydrogenchloride in ethanol; water
T=150°C; 0.0833333 h; Microwave;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2005/67923 A1, 2005 ;
Location in patent: Page/Page column 67 ;
WO 2005/067923 A1
反应条件
ammonia; HATU in methanol; N,N-dimethyl-formamide
T=20°C; 3 h; Product distribution / selectivity;
参考文献
GLAXO GROUP LIMITED
Patent: WO2006/34317 A2, 2006 ;
Location in patent: Page/Page column 75 ;
WO 2006/034317 A2
反应条件
potassium phosphate; 2'-(dimethylamino)-2-biphenylyl-palladium(ll) chloride dinorbornyl-phosphine complex in 1,4-dioxane; water
3 h; Heating / reflux; Product distribution / selectivity;
参考文献
GLAXO GROUP LIMITED
Patent: WO2006/34317 A2, 2006 ;
Location in patent: Page/Page column 75-76 ;
WO 2006/034317 A2
