(R)-3-丁烯-1,2-二醇合成路线 （共 21 条）
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water in tetrahydrofuran
T=0 - 20°C;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
triethyl borane; S,S-DACHN; sodium hydrogencarbonate; 4-(N,N-dimethlyamino)pyridine; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in dichloromethane
Hydrolysis;
参考文献
Trost, Barry M.; McEachern, Ernest J.
Journal of the American Chemical Society, 1999 , vol. 121, # 37 p. 8649 - 8650
反应条件
(AcO)[(S)-substituted salen]Co(III) in water
T=0°C; 12 h; Title compound not separated from byproducts.;
参考文献
Dey, Sangeeta; Powell, Douglas R.; Hu, Chunhua; Berkowitz, David B.
Angewandte Chemie - International Edition, 2007 , vol. 46, # 37 p. 7010 - 7014
反应条件
tert.-butylhydroperoxide; sodium hydride in N,N-dimethyl-formamide
参考文献
Kaviani-Joupari, Makan; Schramm, Michael P.
Tetrahedron Letters, 2013 , vol. 54, # 37 p. 5014 - 5017
反应条件
Pseudomonas putida ML 2; wild type strain in phosphate buffer
T=4°C; Addition; dihydroxylation; pH=7.5; 24 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Boyd, Derek R.; Clarke, David; Cleij, Marcel C.; Hamilton, John T.G.; Sheldrake, Gary N.
Monatshefte fur Chemie, 2000 , vol. 131, # 6 p. 673 - 685
反应条件
[(S,S-N,N'-bis(3,5-bis(tert-butyl)salicylidene)-1,2-cyclohexanediamine)cobalt(II)]; acetic acid in water
18 h;
参考文献
Orac, Crina M.; Zhou, Shu; Means, John A.; Boehm, David; Bergmeier, Stephen C.; Hines, Jennifer V.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6786 - 6795
参考文献
Suzuki; Kasai; Minamiura
Tetrahedron Asymmetry, 1994 , vol. 5, # 2 p. 239 - 246
反应条件
sodium hydroxide; sodium azide; acid phosphatase; pyruvate kinase; Phosphoenolpyruvate; glycerol kinase from Streptomyces canus; potassium chloride; adenosine 5'-triphosphoric acid; 2-hydroxyethanethiol; magnesium chloride
1.) H2O, 35 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Keith Chenault; Chafin, Laura F.; Liehr, Sebastian
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4039 - 4045
参考文献
Rao, Rama A V; Reddy, E Rajathnam; Joshi, Bhalchandra V; Yadav, J S
Tetrahedron Letters, 1987 , vol. 28, # 51 p. 6497 - 6500
反应条件
sulfuric acid
T=5°C; 0.75 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Boaz
Tetrahedron Asymmetry, 1995 , vol. 6, # 1 p. 15 - 16
