反应条件
1: N,N-dimethylaniline / 170 °C
2: 1.) Na/liquid NH3 / 1.) THF, -70 deg C, 30 min, 2.) THF, -70 deg C, 30 min
3: BBr3 / CH2Cl2 / -60 - 20 °C
4: pyridine / 2 h / Heating
View Scheme
参考文献
Angerer, Erwin von; Prekajac, Jelica; Strohmeier, Josef
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1439 - 1447
