1: hexamethylphosphoric acid triamide / 1.) -78 deg C, 30 min; 2.) from -78 deg C to 0 deg C, 90 min 2: 2.) lithium aluminum hydride / 1.) tosylation; View Scheme

1: hexamethylphosphoric acid triamide / 1.) -78 deg C, 30 min; 2.) from -78 deg C to 0 deg C, 90 min 2: saponification View Scheme

1: hexamethylphosphoric acid triamide / 1.) -78 deg C, 30 min; 2.) from -78 deg C to 0 deg C, 90 min 2: 1.) Jones oxidation, 0 deg C; 2.) saponification View Scheme