trifluoroacetic acid 2 h; Heating;

1: 1) HCl, 2) aq. ammonia / 1) CHCl3, -10 deg C, 2) CHCl3, 70 deg C, 90 min, pH = 4.0 2: 20percent aq. NaOH / 2 h / Heating 3: 91 percent / TFA / 2 h / Heating View Scheme

1: 1) HCl, 2) aq. ammonia / 1) CHCl3, -10 deg C, 2) CHCl3, 70 deg C, 90 min, pH = 4.0 2: 20percent aq. NaOH / 2 h / Heating 3: 91 percent / TFA / 2 h / Heating View Scheme

1: 20percent aq. NaOH / 2 h / Heating 2: 91 percent / TFA / 2 h / Heating View Scheme