1: 99 percent / potassium carbonate / dimethylformamide / 14 h / 50 °C 2: 100 percent / Amberlyst 15E / methanol / Heating 3: 85 percent / potassium fluoride / dimethylformamide / 110 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '146024', constants.ctx, '0')">1,3-dibromo-5,5-dimethyl-hydantoin</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a> <br />T=20&deg;C;&nbsp;2&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 100 percent / sulfuric acid / 6 h / Heating<br />2: 62 percent / potassium carbonate / acetonitrile / 16 h / 20 &deg;C<br />3: 100 percent / 1,3-dibromo-5,5-dimethylhydantoin / CHCl₃ / 2 h / 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 62 percent / potassium carbonate / acetonitrile / 16 h / 20 &deg;C<br />2: 100 percent / 1,3-dibromo-5,5-dimethylhydantoin / CHCl₃ / 2 h / 20 &deg;C<br /> <br /> &nbsp;