3-(1,4-二氧杂-8-氮杂螺[4.5]癸烷-8-基)苯硼酸频哪醇酯合成路线 （共 5 条）
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in 1,4-dioxane
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 - 3678
反应条件
1: 85 percent / Et3N / CH2Cl2
2: 40 percent / PdCl2 (dppf); dppf; KOAc / dioxane
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 - 3678
反应条件
1: 89 percent / tetrabutylammonium fluoride / tetrahydrofuran
2: 85 percent / Et3N / CH2Cl2
3: 40 percent / PdCl2 (dppf); dppf; KOAc / dioxane
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 - 3678
反应条件
1: 83 percent / Pd(OAc)2; P(tBu)3; NaOtBu / toluene
2: 89 percent / tetrabutylammonium fluoride / tetrahydrofuran
3: 85 percent / Et3N / CH2Cl2
4: 40 percent / PdCl2 (dppf); dppf; KOAc / dioxane
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 - 3678
反应条件
1: 83 percent / Pd(OAc)2; P(tBu)3; NaOtBu / toluene
2: 89 percent / tetrabutylammonium fluoride / tetrahydrofuran
3: 85 percent / Et3N / CH2Cl2
4: 40 percent / PdCl2 (dppf); dppf; KOAc / dioxane
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Higgins, Guy A.; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3675 - 3678
