噻吩并[3,2-c]吡啶-2-羧酸合成路线 （共 3 条）
反应条件
hydrogenchloride; sodium hydroxide in methanol; water
参考文献
Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Groppi JR., Vincent E.
Patent: US2003/45540 A1, 2003 ;
反应条件
diisopropylamine in tetrahydrofuran; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water; acetone
参考文献
Eli Lilly and Company
Patent: US4501739 A1, 1985 ;
反应条件
1: potassium carbonate / N,N-dimethyl-formamide; water / 45 °C
2: water; lithium hydroxide hydrate / methanol / 20 °C
View Scheme
参考文献
HUTCHISON MEDIPHARMA LIMITED; SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: WO2011/79804 A1, 2011 ;
WO 2011/079804 A1
Title/Abstract Full Text Show Details
SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: US2012/245178 A1, 2012 ;
US 20120245178 A1
