1.1: sodium bis(trimethylsilyl)amide / tetrahydrofuran / 1.17 h / -40 - 20 °C
1.2: 73 percent / tetrahydrofuran / 4 h / 0 °C
2.1: p-toluenesulfonic acid / tetrahydrofuran; H2O / 0.33 h / Heating
3.1: sodium bis(trimetylsilyl)amide / tetrahydrofuran / 1 h / 0 °C
3.2: 53 percent / tetrahydrofuran / -100 - 20 °C
4.1: p-toluenesulfonic acid / tetrahydrofuran; H2O / 0.25 h / Heating
View Scheme
参考文献
Peng, Sheng; Okeley, Nicole M.; Tsai, Ah-Lim; Wu, Gang; Kulmacz, Richard J.; Van der Donk, Wilfred A.
Journal of the American Chemical Society, 2002 , vol. 124, # 36 p. 10785 - 10796
1.1: sodium bis(trimetylsilyl)amide / tetrahydrofuran / 1 h / 0 °C
1.2: 53 percent / tetrahydrofuran / -100 - 20 °C
2.1: p-toluenesulfonic acid / tetrahydrofuran; H2O / 0.25 h / Heating
View Scheme
参考文献
Peng, Sheng; Okeley, Nicole M.; Tsai, Ah-Lim; Wu, Gang; Kulmacz, Richard J.; Van der Donk, Wilfred A.
Journal of the American Chemical Society, 2002 , vol. 124, # 36 p. 10785 - 10796
1.1: TsOH
2.1: sodium bis(trimethylsilyl)amide / tetrahydrofuran / 1.17 h / -40 - 20 °C
2.2: 73 percent / tetrahydrofuran / 4 h / 0 °C
3.1: p-toluenesulfonic acid / tetrahydrofuran; H2O / 0.33 h / Heating
4.1: sodium bis(trimetylsilyl)amide / tetrahydrofuran / 1 h / 0 °C
4.2: 53 percent / tetrahydrofuran / -100 - 20 °C
5.1: p-toluenesulfonic acid / tetrahydrofuran; H2O / 0.25 h / Heating
View Scheme
参考文献
Peng, Sheng; Okeley, Nicole M.; Tsai, Ah-Lim; Wu, Gang; Kulmacz, Richard J.; Van der Donk, Wilfred A.
Journal of the American Chemical Society, 2002 , vol. 124, # 36 p. 10785 - 10796
1.1: p-toluenesulfonic acid / tetrahydrofuran; H2O / 0.33 h / Heating
2.1: sodium bis(trimetylsilyl)amide / tetrahydrofuran / 1 h / 0 °C
2.2: 53 percent / tetrahydrofuran / -100 - 20 °C
3.1: p-toluenesulfonic acid / tetrahydrofuran; H2O / 0.25 h / Heating
View Scheme
参考文献
Peng, Sheng; Okeley, Nicole M.; Tsai, Ah-Lim; Wu, Gang; Kulmacz, Richard J.; Van der Donk, Wilfred A.
Journal of the American Chemical Society, 2002 , vol. 124, # 36 p. 10785 - 10796
