(4R,5S)-(+)-顺-4,5-二苯基-2-恶唑烷酮合成路线 （共 23 条）
反应条件
potassium hydroxide; ammonium cerium(IV) nitrate Yield given;
参考文献
Journal of the American Chemical Society, , vol. 118, # 15 p. 3757 - 3758
反应条件
potassium carbonate 8 h; Heating;
参考文献
Matsui, Satoshi; Hashimoto, Yukihiko; Saigo, Kazuhiko
Synthesis, 1998 , # 8 p. 1161 - 1166
反应条件
1: 1.) n-BuLi, (-)-sparteine 2: 1.) KOH, 2.) ceric ammonium nitrate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 118, # 15 p. 3757 - 3758
反应条件
1: 95 percent / pyridine / tetrahydrofuran / 3 h / -15 °C 2: 95 percent / NaOCH3 / tetrahydrofuran / 12 h / Ambient temperature 3: 11.12 g / Et3N / benzene / 1) reflux, 60h, 2) room temp., 24h 4: 5.95 g / NaOCH3 / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 15 p. 2520 - 2527
反应条件
1: 95 percent / NaOCH3 / tetrahydrofuran / 12 h / Ambient temperature 2: 11.12 g / Et3N / benzene / 1) reflux, 60h, 2) room temp., 24h 3: 5.95 g / NaOCH3 / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 15 p. 2520 - 2527
反应条件
1: 11.12 g / Et3N / benzene / 1) reflux, 60h, 2) room temp., 24h 2: 5.95 g / NaOCH3 / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 15 p. 2520 - 2527
反应条件
sodium methylate in tetrahydrofuran 3 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 48, # 15 p. 2520 - 2527
反应条件
1: trans-4,5-diphenyl-1,3-oxazolidin-2-one With (R)-7-chloro-2-phenyl-2,3-dihydroimidazo[1,2-a]quinoline; N-ethyl-N,N-diisopropylamine in 1,1-dimethylpropan-1-ol T=0°C; Resolution of racemate; 2: isobutyric anhydride in 1,1-dimethylpropan-1-ol T=0°C; 15 h; Resolution of racemate; Reagent/catalystTime; enantioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 134, # 42 p. 17605 - 17612
反应条件
in tetrahydrofuran 3 h; Heating;
参考文献
Badone, Domenico; Bernassau, Jean-Marie; Cardamone, Rosanna; Guzzi, Umberto
Angewandte Chemie, 1996 , vol. 108, # 5 p. 575 - 578
反应条件
1: NaH / tetrahydrofuran / 2 h / 25 °C 2: Cs2CO3 / aq. methanol 3: DIPEA; MsCl / 1,2-dichloro-ethane / 83 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 51 p. 10071 - 10074
