tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; Inert atmosphere;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=-78 - 20&deg;C;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: triethylamine / N,N-dimethyl-formamide / 18 h / 20 &deg;C / Inert atmosphere<br />2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1 h / -78 &deg;C / Inert atmosphere<br />2.2: 2 h / -78 - 20 &deg;C / Inert atmosphere<br /> <br /> &nbsp;