3,4-亚甲基二氧基苯甲酰基甲酸乙酯合成路线 （共 3 条）
反应条件
aluminium trichloride in dichloromethane
T=20°C; Friedel-Crafts acylation; 1 h;
参考文献
Ianni, Alen; Waldvogel, Siegfried R.
Synthesis, 2006 , # 13 p. 2103 - 2112
反应条件
1: 1,2-methylenedioxy-4-bromobenzene With magnesium in tetrahydrofuran
T=20°C; 1 h;
2: oxalic acid diethyl ester in tetrahydrofuran
T=-78 - -10°C; 1 h;
参考文献
Shirai, Tomohiko; Ito, Hajime; Yamamoto, Yasunori
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2658 - 2661
Angew. Chem., 2014 , vol. 126, # 10 p. 2696 - 2699,4
反应条件
1: 89 percent / BTAC / CH2Cl2; H2O / 20 °C
2: 76 percent / LDA / tetrahydrofuran / -78 - 20 °C
View Scheme
参考文献
Thasana, Nopporn; Prachyawarakorn, Vilailak; Tontoolarug, Sopchok; Ruchirawat, Somsak
Tetrahedron Letters, 2003 , vol. 44, # 5 p. 1019 - 1021
