4-甲基-3-(4,4,5,5-四甲基-1,3,2-二氧硼烷)-苯甲腈合成路线 （共 3 条）
反应条件
potassium acetate; palladium diacetate in N,N-dimethyl-formamide
T=80°C; 3 h; Microwave irradiation;
参考文献
SYNTA PHARMACEUTICALS CORP.; CHEN, Shoujun; ZHANG, Junyi; JIANG, Jun; KOWALCZYK-PRZEWLOKA, Teresa; XIA, Zhiqiang; ZHANG, Shijie
Patent: WO2013/63385 A1, 2013 ;
Location in patent: Paragraph 0097-0098 ;
反应条件
caesium carbonate; [2-[(dimethylamino-κN)methyl]phenyl-κC](tricyclohexylphosphine)(trifluoroacetato-κO-(SP-4-3)palladium) in 1,4-dioxane
Suzuki Coupling; 4 h; Heating / reflux;
参考文献
PFIZER LIMITED; PFIZER INC.
Patent: WO2005/28452 A1, 2005 ;
Location in patent: Page/Page column 126 ;
WO 2005/028452 A1
反应条件
bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 4,4'-di-tert-butyl-2,2'-dipyridyl in tetrahydrofuran
T=25°C; 72 h; Title compound not separated from byproducts;
参考文献
Chotana, Ghayoor A.; Rak, Michael A.; Smith, Milton R.
Journal of the American Chemical Society, 2005 , vol. 127, # 30 p. 10539 - 10544
