反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 20 °C
2: di-isopropyl azodicarboxylate / triphenylphosphine / tetrahydrofuran / 20 h / 20 °C
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
4: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 22 h / 20 °C
5: TEAHCO3; tetraethyl ammonium [18]F-fluoride / acetonitrile / 0.17 h / 90 °C
View Scheme
参考文献
LANTHEUS MEDICAL IMAGING, INC.; CESATI, Richard, R.; CHEESMAN, Edward, H.; LAZEWATSKY, Joel; RADEKE, Heike, S.; CASTNER, James, F.; MONGEAU, Enrico; ZDANKIEWICZ, Dianne, D.; SIEGLER, Robert, Wilburn; DEVINE, Marybeth
Patent: WO2011/97649 A2, 2011 ;
