1: aq. NH2OH*HCl; AcONa / ethanol / 12 h
2: N-chlorosuccinimide; pyridine / CHCl3; tetrahydrofuran / 2 h
View Scheme
参考文献
Lam, Patrick Y. S.; Adams, Jessica J.; Clark, Charles G.; Calhoun, W. Jason; Luettgen, Joseph M.; Knabb, Robert M.; Wexler, Ruth R.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1795 - 1799
1: in tetrahydrofuran
T=20°C; 0.0833333 h;
2: With tetrabutyl ammonium fluoride in tetrahydrofuran
T=20°C; 0.00833333 h;
参考文献
Spiteri, Christian; Sharma, Pallavi; Zhang, Fengzhi; MacDonald, Simon J. F.; Keeling, Steve; Moses, John E.
Chemical Communications, 2010 , vol. 46, # 8 p. 1272 - 1274