[2-(4-氯-苯基)-2-羟基-乙基]-氨基甲酸叔丁酯合成路线 (共 2 条)
反应条件
trifluoroacetic acid in dichloromethane T=25°C; 1 h;
参考文献
H. LUNDBECK A/S
Patent: WO2005/87754 A1, 2005 ;
Location in patent: Page/Page column 43-44 ;
WO 2005/087754 A1
反应条件
1: carbamic acid 1,1-dimethylethyl ester With sodium hydroxide in water; acetonitrile
T=0°C; 0.0333333 h;
2: tert-butylhypochlorite in water; acetonitrile
T=0°C; 0.166667 h;
3: para-fluorostyrene With potassium osmate(VI); sodium dihydrogenphosphate; phosphate buffer; [(DHQ)2AQN]
more than 3 stages;
参考文献
H. LUNDBECK A/S
Patent: WO2005/87754 A1, 2005 ;
Location in patent: Page/Page column 43 ;
WO 2005/087754 A1