1: 68 percent / Pd2(dba)3; AsPh3 / 1-methyl-pyrrolidin-2-one / 24 h / 70 °C 2: 70 percent / PdCl2(PPh3)2 / N,N-dimethyl-acetamide / 18 h / 140 °C 3: ClSO2Me; Et3N / CH2Cl2 View Scheme

1: 68 percent / Pd2(dba)3; AsPh3 / 1-methyl-pyrrolidin-2-one / 24 h / 70 °C 2: 70 percent / PdCl2(PPh3)2 / N,N-dimethyl-acetamide / 18 h / 140 °C View Scheme

1: 68 percent / Pd2(dba)3; AsPh3 / 1-methyl-pyrrolidin-2-one / 24 h / 70 °C 2: 70 percent / PdCl2(PPh3)2 / N,N-dimethyl-acetamide / 18 h / 140 °C 3: ClSO2Me; Et3N / CH2Cl2 4: Cs2CO3 / acetonitrile / 20 °C View Scheme

triphenyl-arsane; lithium chloride; tris-(dibenzylideneacetone)dipalladium(0) in various solvent(s) T=80°C; 70 h;

triphenyl-arsane; lithium chloride; tris-(dibenzylideneacetone)dipalladium(0) in various solvent(s) T=80°C; 70 h;

(tBuCN)2CuOTf; 1-Fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate in ethyl acetate T=25°C; 12 h; Inert atmosphereGlovebox;

acrylic acid n-butyl ester; anhydrous lithium acetate; copper diacetate; palladium diacetate in N,N-dimethyl-formamide byproducts: butyl 3-(4-trifluoromethylphenyl)propenoate, (4-CF3C6H4)2; under Ar; 0.30-0.36 mmol of organotin comp. and 0.30 mmol of olefin added to a soln. of 0.03 mmol of Pd(OAc)2, 0.90 mmol of Cu(OAc)2 and 0.60 mmol of LiOAc in DMF at room temp., mixt. stirred at 100° for 24 h, diluted with Et2O; monitored by NMR spectra;

bis(η3-allyl-μ-chloropalladium(II)); 1,5-bis-(diphenylphosphino)-pentane in N,N-dimethyl-formamide T=80°C; Kosugi-Migita-Stille coupling reaction; 72 h;

trifluoroacetic acid; cobalt(II) dibromide; zinc in acetonitrile CoBr2 and Zn dust activated with CF3CO2H reacted for 5 min with allyl chloride in MeCN, aryl halide and tributylstannyl chloride added simultaneously in MeCN at room temp., stirred for 24 h at 50°C;

in acetonitrile-D3 T=25°C; Inert atmosphere; Equilibrium constant;