1,1,1,2,2,3,4,4,5,5,5-十一氟-3-(三氟甲基)戊烷合成路线 (共 1 条)
反应条件
1: (4-methoxybenzyl)triphenylphosphonium chloride in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: N-(3,4,5-trimethoxybenzylidene)-p-toluenesulfonamide in tetrahydrofuran; hexane T=-78 - 20°C; 12 h; Inert atmosphere; optical yield given as percent destereoselective reaction;
参考文献
Dong, De-Jun; Li, Hai-Hua; Tian, Shi-Kai
Journal of the American Chemical Society, 2010 , vol. 132, # 14 p. 5018 - 5020