N-(3,4-环氧基丁基)邻苯二甲酰亚胺合成路线 （共 6 条）
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform
T=20°C; 18 h;
参考文献
Incarvito; Lam; Rhatigan; Rheingold; Jin Qin; Gavrilova; Bosnich
Journal of the Chemical Society, Dalton Transactions, 2001 , # 23 p. 3478 - 3488
反应条件
in N,N-dimethyl-formamide
T=100°C; Gabriel reaction; 0.333333 h; microwave;
参考文献
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
Patent: WO2008/153573 A1, 2008 ;
Location in patent: Page/Page column 20 ;
反应条件
in dichloromethane
T=0 - 20°C; 48 h;
参考文献
Klinge Pharma GmbH
Patent: US6903118 B1, 2005 ;
Location in patent: Page/Page column 162-163 ;
反应条件
1: dimethylformamide
2: m-chloroperbenzoic acid
View Scheme
参考文献
Beppu, Takanobu; Shirahata, Akira; Samejima, Keijiro
Biological and Pharmaceutical Bulletin, 1996 , vol. 19, # 1 p. 1 - 5
反应条件
1: potassium carbonate / acetonitrile / 13 h / 90 °C
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 10 h / 20 °C
View Scheme
参考文献
GREEN CROSS CORPORATION
Patent: US2012/232090 A1, 2012 ;
反应条件
potassium carbonate in ethanol
6 h; Heating;
参考文献
Ahmed; Stratford; Jenkins
Arzneimittel-Forschung/Drug Research, 1985 , vol. 35, # 12 p. 1763 - 1768
