7-(羧甲基)-6-甲基-10-[2-氧代-2-(2-巯基乙基氨基)乙基]-1,4,7,10-四氮杂环十二烷-1,4-二甲酸合成路线 （共 2 条）
反应条件
tri-iso-propylsilane; trifluoroacetic acid
T=20°C; 0.0833333 h;
参考文献
Waengler; Eisenhut; Haberkorn; Mier
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 5 p. 2606 - 2616
反应条件
1: N-hydroxysuccinimide; HBTU / dimethylformamide / 24 h / 20 °C
2: aq. tris(2-carboxyethyl)phosphine hydrochloride / dioxane / pH 7
3: 0.2 g / aq. TFA; triisopropylsilane / 20 h
View Scheme
参考文献
Mattila, Kati; Siltainsuu, Jaana; Balaspiri, Lajos; Ora, Mikko; Loennberg, Harri
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 16 p. 3039 - 3044
