1,1,1-三氟-4-苯基-2-丁酮合成路线 （共 31 条）
反应条件
Co(III) ortho-phenylene-bis(N'-methyloxamidate); oxygen; pivalaldehyde in dichloromethane
参考文献
Blay, Gonzalo; Fernandez, Isabel; Marco-Aleixandre, Alicia; Monje, Belen; Pedro, Jose R; Ruiz, Rafael
Tetrahedron, 2002 , vol. 58, # 42 p. 8565 - 8571
反应条件
[rhodium(I)hydride(PPh3)3] in tetrahydrofuran
Heating;
参考文献
Uma, Ramalinga; Davies, Maxwell K.; Crevisy, Christophe; Gree, Rene
European Journal of Organic Chemistry, 2001 , # 16 p. 3141 - 3146
反应条件
in diethyl ether; toluene
T=-80 - 20°C; 25 h;
参考文献
Yamazaki, Takashi; Terajima, Tsukasa; Kawasaki-Taskasuka, Tomoko
Tetrahedron, 2008 , vol. 64, # 10 p. 2419 - 2424
反应条件
1: oxalyl chloride / CH2Cl2 / 2 h / 20 °C
2: 0.72 g / pyridine / CH2Cl2 / 4 h / -10 °C
View Scheme
参考文献
Yang, Dan; Wong, Man-Kin; Yan, Zheng
Journal of Organic Chemistry, 2000 , vol. 65, # 13 p. 4179 - 4184
反应条件
sodium hydride in tetrahydrofuran
3 h; Inert atmosphereRefluxSchlenk technique; Reagent/catalystTimeTemperatureSolvent;
参考文献
Yang, Dongmei; Zhou, Yuhan; Xue, Na; Qu, Jingping
Journal of Organic Chemistry, 2013 , vol. 78, # 8 p. 4171 - 4176
反应条件
baker's yeast in water
T=35 - 37°C; 240 h;
参考文献
Kitazume, Tomoya; Ishikawa, Nobuo
Chemistry Letters, 1984 , p. 587 - 590
反应条件
1,1,1,3,3,3-hexamethyl-disilazane; sodium hydride in tetrahydrofuran
2 h; Yield given;
参考文献
Begue, Jean-Pierre
Tetrahedron Letters, 1993 , vol. 34, # 48 p. 7753 - 7754
反应条件
1: 1.) Mg / 1.) Et2O, 2.) Et2O, 20 deg C, 20 h
2: 61 percent / H2 / 5percent Pd/C / ethyl acetate / 12 h
View Scheme
参考文献
Gorbunova, M. G.; Gerus, I. I.; Kukhar, V. P.
Journal of Fluorine Chemistry, 1993 , vol. 65, # 1-2 p. 25 - 28
反应条件
1.1: pyridine / dichloromethane / 0 - 20 °C
2.1: cesium fluoride / toluene / 0.17 h / 0 °C
2.2: 24 h / 0 - 20 °C
3.1: tetrabutyl ammonium fluoride; water / tetrahydrofuran; hexane / 2 h / 50 °C
View Scheme
参考文献
Rudzinski, Diandra M.; Kelly, Christopher B.; Leadbeater, Nicholas E.
Chemical Communications, 2012 , vol. 48, # 77 p. 9610 - 9612
反应条件
1.1: cesium fluoride / toluene / 0.17 h / 0 °C
1.2: 24 h / 0 - 20 °C
2.1: tetrabutyl ammonium fluoride; water / tetrahydrofuran; hexane / 2 h / 50 °C
View Scheme
参考文献
Rudzinski, Diandra M.; Kelly, Christopher B.; Leadbeater, Nicholas E.
Chemical Communications, 2012 , vol. 48, # 77 p. 9610 - 9612
