bis(benzonitrile)palladium(II) dichloride; tri-tert-butyl phosphine; diisopropylamine; copper(l) iodide in 1,4-dioxane T=100°C; 40 h;

1: 87 percent / potassium carbonate / dimethylformamide / 24 h / 100 °C 2: 92 percent / tri-t-butylphosphine; diisopropylamine; Pd(PhCN2)Cl2 / CuI / dioxane / 40 h / 100 °C View Scheme

1: 82 percent / potassium carbonate / acetone / 24 h / 55 °C 2: 87 percent / potassium carbonate / dimethylformamide / 24 h / 100 °C 3: 92 percent / tri-t-butylphosphine; diisopropylamine; Pd(PhCN2)Cl2 / CuI / dioxane / 40 h / 100 °C View Scheme