(S)-1-[2-(三氟甲基)苯基]乙胺盐酸盐合成路线 （共 5 条）
反应条件
sodium hydroxide in dichloromethane; water
参考文献
Nugent, Thomas C.; Negru, Daniela E.; El-Shazly, Mohamed; Hu, Dan; Sadiq, Abdul; Bibi, Ahtaram; Umar, M. Naveed
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 2085 - 2092
反应条件
hydrogenchloride in dichloromethane; water
参考文献
Nugent, Thomas C.; Negru, Daniela E.; El-Shazly, Mohamed; Hu, Dan; Sadiq, Abdul; Bibi, Ahtaram; Umar, M. Naveed
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 2085 - 2092
反应条件
1: titanium(IV) isopropylate / isopropanol acetate / 0.5 h / 20 °C
2: hydrogen; palladium/alumina / isopropanol acetate / 24 h / 35 °C / 11251.1 Torr
3: hydrogen; palladium hydroxide on carbon / 48 h / 55 °C / 15001.5 Torr
4: hydrogenchloride / water
View Scheme
参考文献
Nugent, Thomas C.; Marinova, Sofiya M.
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-Z0768-FA, p. 153 - 166
反应条件
1: hydrogen; palladium/alumina / isopropanol acetate / 24 h / 35 °C / 11251.1 Torr
2: hydrogen; palladium hydroxide on carbon / 48 h / 55 °C / 15001.5 Torr
3: hydrogenchloride / water
View Scheme
参考文献
Nugent, Thomas C.; Marinova, Sofiya M.
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-Z0768-FA, p. 153 - 166
反应条件
1: hydrogen; palladium hydroxide on carbon / 48 h / 55 °C / 15001.5 Torr
2: hydrogenchloride / water
View Scheme
参考文献
Nugent, Thomas C.; Marinova, Sofiya M.
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-Z0768-FA, p. 153 - 166
