sodium hydroxide in ethanol T=60°C; 0.0833333 h;

1: 83 percent / POCl3, N,N-diethylaniline / 13 h / 107 °C 2: 58 percent / H2O; acetonitrile / 1 h / 20 °C 3: 72 percent / 1 N aq. NaOH / ethanol / 0.08 h / 60 °C View Scheme

1: 58 percent / H2O; acetonitrile / 1 h / 20 °C 2: 72 percent / 1 N aq. NaOH / ethanol / 0.08 h / 60 °C View Scheme