4-[3-[[(1,1-二甲基乙基)二甲基甲硅烷基]氧基]丙基]苯甲醛合成路线 （共 5 条）
反应条件
sodium formate; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide
T=90°C; 8 h;
参考文献
MERCK FROSST CANADA LTD.
Patent: WO2007/9250 A1, 2007 ;
Location in patent: Page/Page column 58 ;
WO 2007/009250 A1
反应条件
1: (1.1-dimethylethyl)dimethyl[[3-(4-bromophenyl)propyl]oxy]silane With n-butyllithium
T=-78°C;
2: N,N-dimethyl-formamide in tetrahydrofuran
参考文献
Sun, Haiying; Nikolovska-Coleska, Zaneta; Yang, Chao-Yie; Wang, Shaomeng
Tetrahedron Letters, 2005 , vol. 46, # 41 p. 7015 - 7018
反应条件
1.1: NaBH4; I2 / tetrahydrofuran
2.1: Et3N / CH2Cl2
3.1: BuLi / -78 °C
3.2: tetrahydrofuran
View Scheme
参考文献
Sun, Haiying; Nikolovska-Coleska, Zaneta; Yang, Chao-Yie; Wang, Shaomeng
Tetrahedron Letters, 2005 , vol. 46, # 41 p. 7015 - 7018
反应条件
1.1: Et3N / CH2Cl2
2.1: BuLi / -78 °C
2.2: tetrahydrofuran
View Scheme
参考文献
Sun, Haiying; Nikolovska-Coleska, Zaneta; Yang, Chao-Yie; Wang, Shaomeng
Tetrahedron Letters, 2005 , vol. 46, # 41 p. 7015 - 7018
反应条件
1.1: Et3N / CH2Cl2
2.1: BuLi / -78 °C
2.2: tetrahydrofuran
View Scheme
参考文献
Sun, Haiying; Nikolovska-Coleska, Zaneta; Yang, Chao-Yie; Wang, Shaomeng
Tetrahedron Letters, 2005 , vol. 46, # 41 p. 7015 - 7018
