1: With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water T=100°C; 2 h; irradiated in a microwave; 2: With hydrogenchloride in water pH=1;

1: 1.) 17percent ethanolic NH3, 2.) concd. HCl / 1.) from 100 deg C to 110 deg C, 18 h, 2.) reflux, 18 h 2: SOCl2 / 5 h / Heating 3: Heating 4: H2, 10percent HCl / 10percent Pd/C / methanol / 22 h / 760 Torr 5: 5percent methanolic KOH / 1 h / Ambient temperature View Scheme

1: SOCl2 / 1 h / Heating 2: Heating 3: H2, 10percent HCl / 10percent Pd/C / methanol / 22 h / 760 Torr 4: 5percent methanolic KOH / 1 h / Ambient temperature View Scheme