反应条件
1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride in tetrahydrofuran
T=0°C; 0.166667 h;
2: 3,5-bis-(trifluoromethyl)-benzaldehyde in tetrahydrofuran
T=0 - 20°C;
3: With diisobutylaluminium hydride in dichloromethane; toluene
T=-78°C;
参考文献
Zhang, Yinan; Benmohamed, Radhia; Zhang, Wei; Kim, Jinho; Edgerly, Christina K.; Zhu, Yaoqiu; Morimoto, Richard I.; Ferrante, Robert J.; Kirsch, Donald R.; Silverman, Richard B.
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 7 p. 584 - 587
