2-甲氧基-3-乙基-5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)吡啶合成路线 （共 3 条）
反应条件
1: With triethylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in 1,4-dioxane
T=90°C; 36 h;
2: With water in 1,4-dioxane
T=0°C; Product distribution / selectivity;
参考文献
AVENTIS PHARMACEUTICALS INC.
Patent: WO2005/97750 A1, 2005 ;
Location in patent: Page/Page column 59-60; 105 ;
WO 2005/097750 A1
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in dimethyl sulfoxide
T=110°C; 30 h; Product distribution / selectivity;
参考文献
AVENTIS PHARMACEUTICALS INC.
Patent: WO2005/97750 A1, 2005 ;
Location in patent: Page/Page column 59 ;
WO 2005/097750 A1
反应条件
triethylamine in 1,4-dioxane; water
参考文献
SANOFI-AVENTIS DEUTSCHLAND GMBH
Patent: US2007/281948 A1, 2007 ;
