6-酮-1,6-二氢哒嗪-4-羧酸合成路线 （共 6 条）
反应条件
potassium permanganate; sulfuric acid T=45°C; 1 h;
参考文献
ASTRAZENECA AB
Patent: WO2008/41075 A1, 2008 ;
Location in patent: Page/Page column 55 ;
WO 2008/041075 A1
反应条件
hydrogenchloride; water
参考文献
Journal of the American Chemical Society, , vol. 77, p. 3376
反应条件
1: acetic acid; bromine 2: HCl; water View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 3376
反应条件
1: water; N2H4 2: acetic acid; bromine 3: HCl; water View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 3376
参考文献
McMillan; King
Journal of the American Chemical Society, 1955 , vol. 77, p. 3376
反应条件
1: With sulfuric acid 5 h; Heating / reflux; 2: With water; sodium carbonate
参考文献
AstraZeneca AB
Patent: US2009/111822 A1, 2009 ;
Location in patent: Page/Page column 10 ;
US 20090111822 A1
