7-氯-8-氟-2-苯基喹啉合成路线 （共 2 条）
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane
T=-100 - -90°C; 0.1 h;
2: With acetic acid
0.333333 h; Product distribution / selectivity;
参考文献
OSI PHARMACEUTICALS, INC.
Patent: WO2005/97800 A1, 2005 ;
Location in patent: Page/Page column 423-424 ;
WO 2005/097800 A1
反应条件
hydrogenchloride in water; toluene
40 h; Heating / reflux; Product distribution / selectivity;
参考文献
OSI PHARMACEUTICALS, INC.
Patent: WO2005/97800 A1, 2005 ;
Location in patent: Page/Page column 423-424 ;
WO 2005/097800 A1
